The effect of deep brain stimulation randomized by site on balance in Parkinson's disease.

ABSTRACT:

Background

The effect of the surgical site of DBS on balance and gait in Parkinson's Disease (PD) is uncertain. This is the first double-blind study of subjects randomized to either the STN (N = 14) or GPi (N = 14) who were assessed on a range of clinical balance measures.

Methods

Balance testing occurred before and 6 months postsurgery. A control PD group was tested over the same period without surgery (N = 9). All subjects were tested on and off medication and DBS subjects were also tested on and off DBS. The Postural Instability and Gait Disability items of the UPDRS and additional functional tests, which we call the Balance and Gait scale, were assessed. Activities of Balance Confidence and Activities of Daily Living questionnaires were also recorded.

Results

Bala

SUBMITTER: St George RJ 

PROVIDER: S-EPMC4057940 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature