Inflammatory markers and obstructive sleep apnea in obese children: the NANOS study.

ABSTRACT:

Introduction

Obesity and obstructive sleep apnea syndrome (OSA) are common coexisting conditions associated with a chronic low-grade inflammatory state underlying some of the cognitive, metabolic, and cardiovascular morbidities.

Aim

To examine the levels of inflammatory markers in obese community-dwelling children with OSA, as compared to no-OSA, and their association with clinical and polysomnographic (PSG) variables. Methods. In this cross-sectional, prospective multicenter study, healthy obese Spanish children (ages 4-15 years) were randomly selected and underwent nocturnal PSG followed by a morning fasting blood draw. Plasma samples were assayed for multiple inflammatory markers.

Results

204 children were enrolled in the study; 75 had OSA, defined by an obstructiv

SUBMITTER: Gileles-Hillel A 

PROVIDER: S-EPMC4058796 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature