The association between renal function biomarkers and subclinical cardiovascular measures in African Caribbean families.

ABSTRACT:

Background

Risk of cardiovascular disease (CVD) and mortality are increased in people with subclinical CVD. The impact of ethnicity and race on subclinical CVD is substantial. Previous studies assessed the heritability of several renal function biomarkers and their relationship with subclinical CVD among populations of European ancestries, but, to our knowledge, no such data are available in African ancestry populations.

Objective

Our aim was to investigate the relationships between renal function biomarkers and subclinical CVD among Afro-Caribbeans residing on the island of Tobago.

Design and methods

402 participants, aged 18 to 103 years, from seven large, multi-generation pedigrees (average family size: 50; range: 19 to 96; -3500 relative pairs) were included in th

SUBMITTER: Li H 

PROVIDER: S-EPMC4059560 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature