Chemogenesis of an antiangiogenic glycosaminoglycan.

ABSTRACT: In this letter we report a facile chemical conversion of heparin, a potent anticoagulant with minimal antiangiogenic activity, into an effective antiangiogenic glycosaminoglycan through optimized chemical approaches. This work highlights the potential for industrial scale production of a therapeutic anticancer glycosaminoglycan.

SUBMITTER: Raman K 

PROVIDER: S-EPMC4060934 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature