Novel Pharmacologic Approaches to Treating Cannabis Use Disorder.

ABSTRACT: With large and increasing numbers of people using cannabis, the development of cannabis use disorder (CUD) is a growing public health concern. Despite the success of evidence-based psychosocial therapies, low rates of initial abstinence and high rates of relapse during and following treatment for CUD suggest a need for adjunct pharmacotherapies. Here we review the literature on medication development for the treatment of CUD, with a particular focus on studies published within the last three years (2010-2013). Studies in both the human laboratory and in the clinic have tested medications with a wide variety of mechanisms. In the laboratory, the following medication strategies have been shown to decrease cannabis withdrawal and self-administration following a period of abstinence (a model o

SUBMITTER: Balter RE 

PROVIDER: S-EPMC4061701 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature