Comparative analysis of the base compositions of the pre-mRNA 3' cleaved-off region and the mRNA 3' untranslated region relative to the genomic base composition in animals and plants.

ABSTRACT: The precursor messenger RNA (pre-mRNA) three-prime cleaved-off region (3'COR) and the mRNA three-prime untranslated region (3'UTR) play critical roles in regulating gene expression. The differences in base composition between these regions and the corresponding genomes are still largely uncharacterized in animals and plants. In this study, the base compositions of non-redundant 3'CORs and 3'UTRs were compared with the corresponding whole genomes of eleven animals, four dicotyledonous plants, and three monocotyledonous (cereal) plants. Among the four bases (A, C, G, and U for adenine, cytosine, guanine, and uracil, respectively), U (which corresponds to T, for thymine, in DNA) was the most frequent, A the second most frequent, G the third most frequent, and C the least frequent in most of t

SUBMITTER: Li XQ 

PROVIDER: S-EPMC4062462 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature