Neural correlates of emotion regulation in patients with schizophrenia and non-affected siblings.

ABSTRACT:

Background

Patients with schizophrenia often experience problems regulating their emotions. Non-affected relatives show similar difficulties, although to a lesser extent, and the neural basis of such difficulties remains to be elucidated. In the current paper we investigated whether schizophrenia patients, non-affected siblings and healthy controls (HC) exhibit differences in brain activation during emotion regulation.

Methods

All subjects (n = 20 per group) performed an emotion regulation task while they were in an fMRI scanner. The task contained two experimental conditions for the down-regulation of emotions (reappraise and suppress), in which IAPS pictures were used to generate a negative affect. We also assessed whether the groups differed in emotion regulation strategi

SUBMITTER: van der Meer L 

PROVIDER: S-EPMC4062465 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature