Early-life environmental variation affects intestinal microbiota and immune development in new-born piglets.

ABSTRACT:

Background

Early-life environmental variation affects gut microbial colonization and immune competence development; however, the timing and additional specifics of these processes are unknown. The impact of early-life environmental variations, as experienced under real life circumstances, on gut microbial colonization and immune development has not been studied extensively so far. We designed a study to investigate environmental variation, experienced early after birth, to gut microbial colonization and intestinal immune development.

Methodology/principal findings

To investigate effects of early-life environmental changes, the piglets of 16 piglet litters were divided into 3 groups per litter and experimentally treated on day 4 after birth. During the course of the experimen

SUBMITTER: Schokker D 

PROVIDER: S-EPMC4062469 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature