Variable characteristics of bacteriocin-producing Streptococcus salivarius strains isolated from Malaysian subjects.

ABSTRACT:

Background

Salivaricins are bacteriocins produced by Streptococcus salivarius, some strains of which can have significant probiotic effects. S. salivarius strains were isolated from Malaysian subjects showing variable antimicrobial activity, metabolic profile, antibiotic susceptibility and lantibiotic production.

Methodology/principal findings

In this study we report new S. salivarius strains isolated from Malaysian subjects with potential as probiotics. Safety assessment of these strains included their antibiotic susceptibility and metabolic profiles. Genome sequencing using Illumina's MiSeq system was performed for both strains NU10 and YU10 and demonstrating the absence of any known streptococcal virulence determinants indicating that these strains are safe for subsequent

SUBMITTER: Barbour A 

PROVIDER: S-EPMC4062538 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature