External beam accelerated partial breast irradiation yields favorable outcomes in patients with prior breast augmentation.

ABSTRACT:

Purpose

To report outcomes in breast cancer patients with prior breast augmentation treated with external beam accelerated partial breast irradiation (EB-APBI) utilizing intensity-modulated radiotherapy or 3-dimensional conformal radiotherapy, both with IGRT.

Materials and methods

Sixteen stage 0/1 breast cancer patients with previous elective bilateral augmentation were treated post-lumpectomy on institutional EB-APBI trials (01185132 and 01185145 on clinicaltrials.gov). Patients received 38.5 Gy in 10 fractions over five consecutive days. Breast/chest wall pain and cosmesis were rated by patient; cosmesis was additionally evaluated by physician per RTOG criteria.

Results

The median follow-up from accelerated partial breast irradiation (APBI) completion was 23.9 mont

SUBMITTER: Lei RY 

PROVIDER: S-EPMC4062870 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature