Understanding the sub-cellular dynamics of silicon transportation and synthesis in diatoms using population-level data and computational optimization.
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ABSTRACT: Controlled synthesis of silicon is a major challenge in nanotechnology and material science. Diatoms, the unicellular algae, are an inspiring example of silica biosynthesis, producing complex and delicate nano-structures. This happens in several cell compartments, including cytoplasm and silica deposition vesicle (SDV). Considering the low concentration of silicic acid in oceans, cells have developed silicon transporter proteins (SIT). Moreover, cells change the level of active SITs during one cell cycle, likely as a response to the level of external nutrients and internal deposition rates. Despite this topic being of fundamental interest, the intracellular dynamics of nutrients and cell regulation strategies remain poorly understood. One reason is the difficulties in measurements and mani
SUBMITTER: Javaheri N
PROVIDER: S-EPMC4063665 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
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