How are patients with type 2 diabetes and renal disease monitored and managed? Insights from the observational OREDIA study.

ABSTRACT:

Background and aim

Chronic kidney disease (CKD) is frequent in type 2 diabetes mellitus (T2DM), and therapeutic management of diabetes is more challenging in patients with renal impairment (RI). The place of metformin is of particular interest since most scientific societies now recommend using half the dosage in moderate RI and abstaining from use in severe RI, while the classic contraindication with RI has not been removed from the label. This study aimed to assess the therapeutic management, in particular the use of metformin, of T2DM patients with CKD in real life.

Methods

This was a French cross-sectional observational study: 3,704 patients with T2DM diagnosed for over 1 year and pharmacologically treated were recruited in two cohorts (two-thirds were considered to have

SUBMITTER: Penfornis A 

PROVIDER: S-EPMC4063863 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature