HIV-1 diversity and drug-resistant mutations in infected individuals in Changchun, China.

ABSTRACT:

Objectives

Human immunodeficiency virus type 1 (HIV-1) infection has been detected in all provinces of China. Although epidemiological and phylogenetic studies have been conducted in many regions, such analyses are lacking from Jilin province in northeastern China.

Method

Epidemiological and phylogenetic analyses, as well as detection of drug-resistant mutations, were conducted on 57 HIV-1 infected patients from Changchun city identified and confirmed through annual surveillance by local Centers for Disease Control in Jilin province of northeastern China in 2012.

Results

Sexual contact was determined to be the major pathway for HIV-1 transmission in Jilin, where hetero- and homosexual activities contributed almost equally. Phylogenetic analyses detected multiple subty

SUBMITTER: Yan M 

PROVIDER: S-EPMC4063969 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature