Allergen specific immunotherapy has no influence on standard chemistry and hematology laboratory parameters in clinical studies.

ABSTRACT:

Background

A set of standard clinical chemistry and hematology parameters are usually measured during clinical studies. The major outcome of these standard tests is to control that the drug investigated does not lead to pathophysiological changes in respective organs or blood. In some cases based on scientific rationale such tests may not be needed. In this paper we report on a standard set of clinical chemistry and hematology laboratory parameters measured before and after treatment in three different immunotherapy studies, representing different routes of administration and different formulations.

Methods

Thirteen hematological laboratory parameters and eight clinical chemistry parameters were evaluated from three double-blind, placebo-controlled, randomized, multi-centre,

SUBMITTER: Hafner D 

PROVIDER: S-EPMC4064516 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature