A rapid route to aminocyclopropanes via carbamatoorganozinc carbenoids.

ABSTRACT: Easy as 1,2,3: Reaction of methyl carbamate, triethyl orthoformate, and readily available alkenes provides a highly practical preparation of protected aminocyclopropanes. The reaction proceeds with preferential cis addition to alkenes, and cleavage of the methyl carbamate gives the free aminocyclopropanes as their HI salts.

SUBMITTER: Ishikawa S 

PROVIDER: S-EPMC4065353 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature