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ABSTRACT: Objective
To systematically review the literature for evidence of smoking and alcohol intake as independent risk factors for invasive pneumococcal disease (IPD).Design
Systematic review.Methods
MEDLINE (1946-May 2012) and EMBASE (1947-May 2012) were searched for studies investigating alcohol or smoking as risk factors for acquiring IPD and which reported results as relative risk. Studies conducted exclusively in clinical risk groups, those assessing risk factors for outcomes other than acquisition of IPD and studies describing risk factors without quantifying a relative risk were excluded.Results
Seven observational studies were identified and reviewed; owing to the heterogeneity of study design, meta-analysis was not attempted. Five of six studies investiga
SUBMITTER: Cruickshank HC
PROVIDER: S-EPMC4067833 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature