Multiparametric MRI followed by targeted prostate biopsy for men with suspected prostate cancer: a clinical decision analysis.

ABSTRACT:

Objective

To compare the diagnostic outcomes of the current approach of transrectal ultrasound (TRUS)-guided biopsy in men with suspected prostate cancer to an alternative approach using multiparametric MRI (mpMRI), followed by MRI-targeted biopsy if positive.

Design

Clinical decision analysis was used to synthesise data from recently emerging evidence in a format that is relevant for clinical decision making.

Population

A hypothetical cohort of 1000 men with suspected prostate cancer.

Interventions

mpMRI and, if positive, MRI-targeted biopsy compared with TRUS-guided biopsy in all men.

Outcome measures

We report the number of men expected to undergo a biopsy as well as the numbers of correctly identified patients with or without prostate cancer. A proba

SUBMITTER: Willis SR 

PROVIDER: S-EPMC4067835 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature