Returning individual research results for genome sequences of pancreatic cancer.

ABSTRACT:

Background

Disclosure of individual results to participants in genomic research is a complex and contentious issue. There are many existing commentaries and opinion pieces on the topic, but little empirical data concerning actual cases describing how individual results have been returned. Thus, the real life risks and benefits of disclosing individual research results to participants are rarely if ever presented as part of this debate.

Methods

The Australian Pancreatic Cancer Genome Initiative (APGI) is an Australian contribution to the International Cancer Genome Consortium (ICGC), that involves prospective sequencing of tumor and normal genomes of study participants with pancreatic cancer in Australia. We present three examples that illustrate different facets of how resea

SUBMITTER: Johns AL 

PROVIDER: S-EPMC4067993 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature