Three-dimensional assessment of vascular and perivascular characteristics in subjects with retinopathy of prematurity.

ABSTRACT:

Purpose

To study vascular features detected with spectral domain optical coherence tomography (SD-OCT) in subjects undergoing retinopathy of prematurity (ROP) screening.

Design

Cross-sectional study.

Participants and controls

Fifty-seven premature neonates, 10 with plus disease in at least 1 eye and 47 without plus disease.

Methods

Bedside noncontact SD-OCT imaging was performed after obtaining parental consent on 97 consecutive infants between January 2009 and September 2012. Fifty-seven subjects (31-49 weeks' post-menstrual age) who had an SD-OCT scan in at least 1 eye showing the edge of the optic nerve and at least 1 major retinal vascular arcade were included. One eye per subject was randomly selected for analysis. Two masked graders evaluated scans for (1

SUBMITTER: Maldonado RS 

PROVIDER: S-EPMC4070381 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature