Genome-wide analysis of regulatory proteases sequences identified through bioinformatics data mining in Taenia solium.

ABSTRACT:

Background

Cysticercosis remains a major neglected tropical disease of humanity in many regions, especially in sub-Saharan Africa, Central America and elsewhere. Owing to the emerging drug resistance and the inability of current drugs to prevent re-infection, identification of novel vaccines and chemotherapeutic agents against Taenia solium and related helminth pathogens is a public health priority. The T. solium genome and the predicted proteome were reported recently, providing a wealth of information from which new interventional targets might be identified. In order to characterize and classify the entire repertoire of protease-encoding genes of T. solium, which act fundamental biological roles in all life processes, we analyzed the predicted proteins of this cestode through a

SUBMITTER: Yan HB 

PROVIDER: S-EPMC4070553 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature