Evolutionary game theory for physical and biological scientists. I. Training and validating population dynamics equations.

ABSTRACT: Failure to understand evolutionary dynamics has been hypothesized as limiting our ability to control biological systems. An increasing awareness of similarities between macroscopic ecosystems and cellular tissues has inspired optimism that game theory will provide insights into the progression and control of cancer. To realize this potential, the ability to compare game theoretic models and experimental measurements of population dynamics should be broadly disseminated. In this tutorial, we present an analysis method that can be used to train parameters in game theoretic dynamics equations, used to validate the resulting equations, and used to make predictions to challenge these equations and to design treatment strategies. The data analysis techniques in this tutorial are adapted from the

SUBMITTER: Liao D 

PROVIDER: S-EPMC4071513 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature