Serum cotinine and whole blood folate concentrations in pregnancy.

ABSTRACT:

Purpose

Prenatal tobacco smoke exposure may be associated with low maternal folate levels that increase the risk of adverse infant and child health outcomes by reducing folate availability during fetal development.

Methods

Using data from the Health Outcomes and Measures of the Environment Study, we examined the relationship between secondhand or active tobacco smoke exposure and whole blood folate concentrations in pregnant women from Cincinnati, Ohio (n = 362) at approximately 16-week gestation. We used multivariable linear regression to examine the association between continuous or categorical serum cotinine levels and whole blood folate levels, adjusting for sociodemographic, dietary, and perinatal variables.

Results

After adjustment for potential confounders, an

SUBMITTER: Prasodjo A 

PROVIDER: S-EPMC4071615 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature