Infection hospitalization increases risk of dementia in the elderly.

ABSTRACT:

Objectives

Severe infections, often requiring ICU admission, have been associated with persistent cognitive dysfunction. Less severe infections are more common and whether they are associated with an increased risk of dementia is unclear. We determined the association of pneumonia hospitalization with risk of dementia in well-functioning older adults.

Design

Secondary analysis of a randomized multicenter trial to determine the effect of Gingko biloba on incident dementia.

Setting

Five academic medical centers in the United States.

Subjects

Healthy community volunteers (n = 3,069) with a median follow-up of 6.1 years.

Interventions

None.

Measurement and main results

We identified pneumonia hospitalizations using International Classification of Dise

SUBMITTER: Tate JA 

PROVIDER: S-EPMC4071960 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature