Gene microarray analysis of the lncRNA expression profile in human urothelial carcinoma of the bladder.

ABSTRACT:

Objective

To analyze the expression profile variation of lncRNAs in normal urinary bladder tissue and urothelial carcinoma of the urinary bladder through microarray technology. The differentially expressed lncRNAs were identified and classified, and their biological information was analyzed. The data obtained in the study will prove helpful for the diagnosis, treatment, and prevention of urothelial carcinoma of the bladder.

Materials and methods

Three specimens of urothelial carcinoma of the bladder and three specimens of normal bladder tissue were identified by histology. The total RNA was isolated from the bladder urothelial carcinomas and normal tissue and purified. The targets were mixed and hybridized with the genes on the microarray, which contained thirty thousand lnc

SUBMITTER: Luo H 

PROVIDER: S-EPMC4073740 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature