Update on benefit of immunotherapy and targeted therapy in melanoma: the changing landscape.

ABSTRACT: Malignant melanoma is on the rise. There have been recent advances in targeted agents and immunotherapies that have improved the management and treatment of patients with advanced melanoma. This review discusses the clinical efficacy and unique side effects of targeted immunotherapy and the role of predictive biomarkers in better selection of patients who would derive most benefit from specific treatments. Additionally, this review addresses concerns about the best sequencing algorithms for the currently available targeted agents. By thoroughly and extensively researching through PubMed and the American Society of Clinical Oncology, 69 published articles and abstracts were identified as addressing topics related to malignant melanoma and immunotherapy. The research was divided into subcate

SUBMITTER: Srivastava N 

PROVIDER: S-EPMC4073973 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature