Trends in glyburide compared with insulin use for gestational diabetes treatment in the United States, 2000-2011.

ABSTRACT:

Objective

To describe trends and identify factors associated with choice of pharmacotherapy for gestational diabetes (GDM) from 2000-2011 using a healthcare claims database.

Methods

This was a retrospective cohort study of a large nationwide population of commercially insured women with GDM and pharmacy claims for glyburide or insulin before delivery, 2000-2011. We excluded women younger than 15 years or older than 50 years, those with prior noninsulin-dependent diabetes mellitus, or those who had multiple gestations. We estimated trends over time in the use of glyburide compared with insulin and prevalence ratios and 95% confidence intervals (CIs) for the association between covariates of interest and treatment with glyburide compared with insulin.

Results

We identif

SUBMITTER: Camelo Castillo W 

PROVIDER: S-EPMC4075168 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature