Ontology highlight
ABSTRACT:
SUBMITTER: Okudela K
PROVIDER: S-EPMC4076198 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
PloS one 20140630 6
Small non-protein coding RNA, microRNA (miR), which regulate messenger RNA levels, have recently been identified, and may play important roles in the pathogenesis of various diseases. The present study focused on miR-31 and investigated its potential involvement in lung carcinogenesis. The expression of miR-31 was altered in lung cancer cells through either the amplification or loss of the host gene locus. The strong expression of miR-31 in large cell carcinomas was attributed to the gene amplif ...[more]