A computational study of whole-brain connectivity in resting state and task fMRI.

ABSTRACT:

Background

We compared the functional brain connectivity produced during resting-state in which subjects were not actively engaged in a task with that produced while they actively performed a visual motion task (task-state).

Material and methods

In this paper we employed graph-theoretical measures and network statistics in novel ways to compare, in the same group of human subjects, functional brain connectivity during resting-state fMRI with brain connectivity during performance of a high level visual task. We performed a whole-brain connectivity analysis to compare network statistics in resting and task states among anatomically defined Brodmann areas to investigate how brain networks spanning the cortex changed when subjects were engaged in task performance.

Results

SUBMITTER: Goparaju B 

PROVIDER: S-EPMC4076230 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature