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Environmental risk factors and amyotrophic lateral sclerosis (ALS): a case-control study of ALS in Michigan.


ABSTRACT: An interim report of a case-control study was conducted to explore the role of environmental factors in the development of amyotrophic lateral sclerosis (ALS). Sixty-six cases and 66 age- and gender-matched controls were recruited. Detailed information regarding residence history, occupational history, smoking, physical activity, and other factors was obtained using questionnaires. The association of ALS with potential risk factors, including smoking, physical activity and chemical exposure, was investigated using conditional logistic regression models. As compared to controls, a greater number of our randomly selected ALS patients reported exposure to fertilizers to treat private yards and gardens and occupational exposure to pesticides in the last 30 years than our randomly selected cont

SUBMITTER: Yu Y 

PROVIDER: S-EPMC4076303 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature