Integration of cardiac proteome biology and medicine by a specialized knowledgebase.

ABSTRACT:

Rationale

Omics sciences enable a systems-level perspective in characterizing cardiovascular biology. Integration of diverse proteomics data via a computational strategy will catalyze the assembly of contextualized knowledge, foster discoveries through multidisciplinary investigations, and minimize unnecessary redundancy in research efforts.

Objective

The goal of this project is to develop a consolidated cardiac proteome knowledgebase with novel bioinformatics pipeline and Web portals, thereby serving as a new resource to advance cardiovascular biology and medicine.

Methods and results

We created Cardiac Organellar Protein Atlas Knowledgebase (COPaKB; www.HeartProteome.org), a centralized platform of high-quality cardiac proteomic data, bioinformatics tools, and relev

SUBMITTER: Zong NC 

PROVIDER: S-EPMC4076475 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature