Solid-phase-supported synthesis of morpholinoglycine oligonucleotide mimics.

ABSTRACT: An efficient solid-phase-supported peptide synthesis (SPPS) of morpholinoglycine oligonucleotide (MorGly) mimics has been developed. The proposed strategy includes a novel specially designed labile linker group containing the oxalyl residue and the 2-aminomethylmorpholino nucleoside analogues as first subunits.

SUBMITTER: Abramova TV 

PROVIDER: S-EPMC4077379 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature