Effect of M1a and M1b category in metastatic colorectal cancer.

ABSTRACT:

Background

In 2009, the American Joint Committee on Cancer version 7 staging system introduced the M1 subclassifications M1a (single metastatic site) and M1b (peritoneal or multiple metastatic sites). The study objectives were to evaluate the prognostic effect of site of metastasis and M1a/b category among patients with newly diagnosed colorectal cancer and synchronous metastasis.

Patients and methods

Patients with newly diagnosed pathologic or clinical category M1 colorectal cancer referred to the British Columbia Cancer Agency between 1999 and 2007 were included. Demographic, tumor, treatment, and outcome data were prospectively collected, and prognostic factors were identified. Univariate Cox models were used to assess the prognostic impact of individual sites of metastas

SUBMITTER: Kennecke H 

PROVIDER: S-EPMC4077443 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature