Evaluation of early weight loss thresholds for identifying nonresponders to an intensive lifestyle intervention.

ABSTRACT:

Objective

Weight losses in lifestyle interventions are variable, yet prediction of long-term success is difficult. The utility of using various weight loss thresholds in the first 2 months of treatment for predicting 1-year outcomes was examined.

Methods

Participants included 2327 adults with type 2 diabetes (BMI:35.8 ± 6.0) randomized to the intensive lifestyle intervention (ILI) of the Look AHEAD trial. ILI included weekly behavioral sessions designed to increase physical activity and reduce caloric intake. 1-month, 2-month, and 1-year weight changes were calculated.

Results

Participants failing to achieve a ≥2% weight loss at Month 1 were 5.6 (95% CI:4.5, 7.0) times more likely to also not achieve a ≥10% weight loss at Year 1, compared to those losing ≥2% initially

SUBMITTER: Unick JL 

PROVIDER: S-EPMC4077939 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature