Magnetic Resonance-Guided Focused Ultrasound for Treatment of Myomas - Results of the First Radiology-Gynaecology Experts Meeting.
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ABSTRACT:
SUBMITTER: Beck A
PROVIDER: S-EPMC4078213 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Publications
Magnetic Resonance-Guided Focused Ultrasound for Treatment of Myomas - Results of the First Radiology-Gynaecology Experts Meeting.
Beck A A David M M Kröncke T T
Geburtshilfe und Frauenheilkunde 20140501 5
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Project description:The ability to focus acoustic energy through the intact skull on to targets millimeters in size represents an important milestone in the development of neurotherapeutics. Magnetic resonance-guided focused ultrasound (MRgFUS) is a novel, noninvasive method, which--under real-time imaging and thermographic guidance--can be used to generate focal intracranial thermal ablative lesions and disrupt the blood-brain barrier. An established treatment for bone metastases, uterine fibroids, and breast lesions, MRgFUS has now been proposed as an alternative to open neurosurgical procedures for a wide variety of indications. Studies investigating intracranial MRgFUS range from small animal preclinical experiments to large, late-phase randomized trials that span the clinical spectrum from movement disorders, to vascular, oncologic, and psychiatric applications. We review the principles of MRgFUS and its use for brain-based disorders, and outline future directions for this promising technology.
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