Effect of protective ventilation on postoperative pulmonary complications in patients undergoing general anaesthesia: a meta-analysis of randomised controlled trials.

ABSTRACT:

Objective

To determine whether anaesthetised patients undergoing surgery could benefit from intraoperative protective ventilation strategies.

Methods

MEDLINE, EMBASE and Cochrane Central Register of Controlled Trials (CENTRAL) were searched up to February 2014. Eligible studies evaluated protective ventilation versus conventional ventilation in anaesthetised patients without lung injury at the onset of mechanical ventilation. The primary outcome was the incidence of postoperative pulmonary complications. Included studies must report at least one of the following end points: the incidence of atelectasis or acute lung injury or pulmonary infections.

Results

Four studies (594 patients) were included. Meta-analysis using a random effects model showed a significant decreas

SUBMITTER: Tao T 

PROVIDER: S-EPMC4078782 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature