Derivation of urine output thresholds that identify a very high risk of AKI in patients with septic shock.

ABSTRACT:

Background and objectives

To promote early detection of AKI, recently proposed pretest probability models combine sub-Kidney Disease Improving Global Outcomes (KDIGO) AKI criteria with baseline AKI risk. The primary objective of this study was to determine sub-KDIGO thresholds that identify patients with septic shock at highest risk for AKI.

Design, setting, participants, & measurements

This was a retrospective analysis of 390 adult patients admitted to the medical intensive care unit (ICU) of a tertiary, academic medical center with septic shock between January 2008 and December 2010. Hourly urine output was collected from the time of septic shock recognition (hour 0) to hour 96, urine catheter removal, or ICU discharge (whichever occurred first). All available serum creati

SUBMITTER: Leedahl DD 

PROVIDER: S-EPMC4078959 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature