Differential impact of anxiety symptoms and anxiety disorders on treatment outcome for psychotic depression in the STOP-PD study.

ABSTRACT:

Background

There are conflicting results on the impact of anxiety on depression outcomes. The impact of anxiety has not been studied in major depression with psychotic features ("psychotic depression").

Aims

We assessed the impact of specific anxiety symptoms and disorders on the outcomes of psychotic depression.

Methods

We analyzed data from the Study of Pharmacotherapy for Psychotic Depression that randomized 259 younger and older participants to either olanzapine plus placebo or olanzapine plus sertraline. We assessed the impact of specific anxiety symptoms from the Brief Psychiatric Rating Scale ("tension", "anxiety" and "somatic concerns" and a composite anxiety score) and diagnoses (panic disorder and GAD) on psychotic depression outcomes using linear or logisti

SUBMITTER: Davies SJ 

PROVIDER: S-EPMC4078996 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature