Adiposity, gut microbiota and faecal short chain fatty acids are linked in adult humans.

ABSTRACT:

Background/objectives

High dietary fibre intakes may protect against obesity by influencing colonic fermentation and the colonic microbiota. Though, recent studies suggest that increased colonic fermentation contributes to adiposity. Diet influences the composition of the gut microbiota. Previous research has not evaluated dietary intakes, body mass index (BMI), faecal microbiota and short chain fatty acid (SCFA) in the same cohort. Our objectives were to compare dietary intakes, faecal SCFA concentrations and gut microbial profiles in healthy lean (LN, BMI⩽25) and overweight or obese (OWOB, BMI>25) participants.

Design

We collected demographic information, 3-day diet records, physical activity questionnaires and breath and faecal samples from 94 participants of whom 52 were

SUBMITTER: Fernandes J 

PROVIDER: S-EPMC4079931 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature