Infection routes matter in population-specific responses of the red flour beetle to the entomopathogen Bacillus thuringiensis.

ABSTRACT:

Background

Pathogens can infect their hosts through different routes. For studying the consequences for host resistance, we here used the entomopathogen Bacillus thuringiensis and the red flour beetle Tribolium castaneum for oral and systemic (i. e. pricking the cuticle) experimental infection. In order to characterize the molecular mechanisms underpinning the two different infection routes, the transcriptomes of beetles of two different T. castaneum populations--one recently collected population (Cro1) and a commonly used laboratory strain (SB)--were analyzed using a next generation RNA sequencing approach.

Results

The genetically more diverse population Cro1 showed a significantly larger number of differentially expressed genes. While both populations exhibited similar rea

SUBMITTER: Behrens S 

PROVIDER: S-EPMC4079954 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature