Ontology highlight
ABSTRACT:
SUBMITTER: An JY
PROVIDER: S-EPMC4080319 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
An J Y JY Cristino A S AS Zhao Q Q Edson J J Williams S M SM Ravine D D Wray J J Marshall V M VM Hunt A A Whitehouse A J O AJ Claudianos C C
Translational psychiatry 20140603
The hypothetical 'AXAS' gene network model that profiles functional patterns of heterogeneous DNA variants overrepresented in autism spectrum disorder (ASD), X-linked intellectual disability, attention deficit and hyperactivity disorder and schizophrenia was used in this current study to analyze whole exome sequencing data from an Australian ASD cohort. An optimized DNA variant filtering pipeline was used to identify loss-of-function DNA variations. Inherited variants from parents with a broader ...[more]