Association between source-specific particulate matter air pollution and hs-CRP: local traffic and industrial emissions.

ABSTRACT:

Background

Long-term exposures to particulate matter air pollution (PM2.5 and PM10) and high traffic load have been associated with markers of systemic inflammation. Epidemiological investigations have focused primarily on total PM, which represents a mixture of pollutants originating from different sources.

Objective

We investigated associations between source-specific PM and high-sensitive C-reactive protein (hs-CRP), an independent predictor of cardiovascular disease.

Methods

We used data from the first (2000-2003) and second examination (2006-2008) of the Heinz Nixdorf Recall study, a prospective population-based German cohort of initially 4,814 participants (45-75 years of age). We estimated residential long-term exposure to local traffic- and industry-specific f

SUBMITTER: Hennig F 

PROVIDER: S-EPMC4080540 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature