Functional outcomes in pediatric severe sepsis: further analysis of the researching severe sepsis and organ dysfunction in children: a global perspective trial.

ABSTRACT:

Objectives

To evaluate risk factors for poor functional outcome in 28-day survivors after an episode of severe sepsis.

Design

Retrospective cohort study examining data from the Researching Severe Sepsis and Organ Dysfunction in Children: A Global Perspective trial (NCT00049764).

Setting

One hundred and four pediatric centers in 18 countries.

Subjects

Children with severe sepsis who required both vasoactive-inotropic infusions and mechanical ventilation and who survived to 28 days (n = 384).

Interventions

None.

Measurements and main results

Poor functional outcome was defined as a Pediatric Overall Performance Category score greater than or equal to 3 and an increase from baseline when measured 28 days after trial enrollment. Median Pediatric Overa

SUBMITTER: Farris RW 

PROVIDER: S-EPMC4080839 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature