Likelihood ratios for glaucoma diagnosis using spectral-domain optical coherence tomography.

ABSTRACT:

Purpose

To present a methodology for calculating likelihood ratios for glaucoma diagnosis for continuous retinal nerve fiber layer (RNFL) thickness measurements from spectral-domain optical coherence tomography (spectral-domain OCT).

Design

Observational cohort study.

Methods

A total of 262 eyes of 187 patients with glaucoma and 190 eyes of 100 control subjects were included in the study. Subjects were recruited from the Diagnostic Innovations Glaucoma Study. Eyes with preperimetric and perimetric glaucomatous damage were included in the glaucoma group. The control group was composed of healthy eyes with normal visual fields from subjects recruited from the general population. All eyes underwent RNFL imaging with Spectralis spectral-domain OCT. Likelihood ratios for g

SUBMITTER: Lisboa R 

PROVIDER: S-EPMC4081013 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature