Temporal and spatial temperature measurement in insulator-based dielectrophoretic devices.

ABSTRACT: Insulator-based dielectrophoresis is a relatively new analytical technique with a large potential for a number of applications, such as sorting, separation, purification, fractionation, and preconcentration. The application of insulator-based dielectrophoresis (iDEP) for biological samples, however, requires the precise control of the microenvironment with temporal and spatial resolution. Temperature variations during an iDEP experiment are a critical aspect in iDEP since Joule heating could lead to various detrimental effects hampering reproducibility. Additionally, Joule heating can potentially induce thermal flow and more importantly can degrade biomolecules and other biological species. Here, we investigate temperature variations in iDEP devices experimentally employing the thermosensi

SUBMITTER: Nakano A 

PROVIDER: S-EPMC4082381 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature