Quantitative optical coherence tomography angiography of choroidal neovascularization in age-related macular degeneration.

ABSTRACT:

Purpose

To detect and quantify choroidal neovascularization (CNV) in patients with age-related macular degeneration (AMD) using optical coherence tomography (OCT) angiography.

Design

Observational, cross-sectional study.

Participants

A total of 5 normal subjects and 5 subjects with neovascular AMD were included.

Methods

A total of 5 eyes with neovascular AMD and 5 normal age-matched controls were scanned by a high-speed (100 000 A-scans/seconds) 1050-nm wavelength swept-source OCT. The macular angiography scan covered a 3 × 3-mm area and comprised 200 × 200 × 8 A-scans acquired in 3.5 seconds. Flow was detected using the split-spectrum amplitude-decorrelation angiography (SSADA) algorithm. Motion artifacts were removed by 3-dimensional (3D) orthogonal registrat

SUBMITTER: Jia Y 

PROVIDER: S-EPMC4082740 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature