A multicenter approach evaluating the impact of vitamin e-blended polyethylene in cementless total hip replacement.

ABSTRACT: Since polyethylene is one of the most frequently used biomaterials as a liner in total hip arthroplasty, strong efforts have been made to improve design and material properties over the last 50 years. Antioxidants seems to be a promising alternative to further increase durability and reduce polyethylene wear in long term. As of yet, only in vitro results are available. While they are promising, there is yet no clinical evidence that the new material shows these advantages in vivo. To answer the question if vitamin-E enhanced ultra-high molecular weight polyethylene (UHMWPE) is able to improve long-term survivorship of cementless total hip arthroplasty we initiated a randomized long-term multicenter trial. Designed as a superiority study, the oxidation index assessed in retrieval analyses o

SUBMITTER: Jager M 

PROVIDER: S-EPMC4083306 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature