Evolution of the Pax-Six-Eya-Dach network: the calcisponge case study.

ABSTRACT:

Background

The Pax-Six-Eya-Dach network (PSEDN) is involved in a variety of developmental processes, including well documented roles in determination of sensory organs and morphogenesis in bilaterian animals. Expression of PSEDN components in cnidarians is consistent with function in sensory organ development. Recent work in demosponges demonstrated the presence of single homologs of Pax and Six genes, and their possible involvement in morphogenesis, but the absence of the remaining network components. Calcisponges are evolutionarily distant from demosponges, and the developmental toolkits of these two lineages differ significantly. We used an emerging model system, Sycon ciliatum, to identify components of the PSEDN and study their expression during embryonic and postembryonic dev

SUBMITTER: Fortunato SA 

PROVIDER: S-EPMC4083861 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature