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Efficient generation and increased reactivity in cationic gold via Bronsted acid or Lewis acid assisted activation of an imidogold precatalyst.

ABSTRACT: Brønsted or Lewis acid assisted activation of an imidogold precatalyst (L-Au-Pht, Pht = phthalimide) offers a superior way to generate cationic gold compared with the commonly used silver-based system. It is also broadly applicable for most common gold-catalyzed reactions. For reactions that require milder conditions, milder acids can be used for optimized efficiency.

SUBMITTER: Han J

PROVIDER: S-EPMC4084832 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature

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Efficient generation and increased reactivity in cationic gold via Brønsted acid or Lewis acid assisted activation of an imidogold precatalyst.

Han Junbin J Shimizu Naoto N Lu Zhichao Z Amii Hideki H Hammond Gerald B GB Xu Bo B

Organic letters 20140623 13

Brønsted or Lewis acid assisted activation of an imidogold precatalyst (L-Au-Pht, Pht = phthalimide) offers a superior way to generate cationic gold compared with the commonly used silver-based system. It is also broadly applicable for most common gold-catalyzed reactions. For reactions that require milder conditions, milder acids can be used for optimized efficiency. ...[more]

PMID: 24956218

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