Attitudes of genetics professionals toward the return of incidental results from exome and whole-genome sequencing.

ABSTRACT: Professional recommendations for the return of results from exome and whole-genome sequencing (ES/WGS) have been controversial. The lack of clear guidance about whether and, if so, how to return ES/WGS incidental results limits the extent to which individuals and families might benefit from ES/WGS. The perspectives of genetics professionals, particularly those at the forefront of using ES/WGS in clinics, are largely unknown. Data on stakeholder perspectives could help clarify how to weigh expert positions and recommendations. We conducted an online survey of 9,857 genetics professionals to learn their attitudes on the return of incidental results from ES/WGS and the recent American College of Medical Genetic and Genomics Recommendations for Reporting of Incidental Findings in Clinical Exom

SUBMITTER: Yu JH 

PROVIDER: S-EPMC4085580 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature