StemCellNet: an interactive platform for network-oriented investigations in stem cell biology.

ABSTRACT: Stem cells are characterized by their potential for self-renewal and their capacity to differentiate into mature cells. These two key features emerge through the interplay of various factors within complex molecular networks. To provide researchers with a dedicated tool to investigate these networks, we have developed StemCellNet, a versatile web server for interactive network analysis and visualization. It rapidly generates focused networks based on a large collection of physical and regulatory interactions identified in human and murine stem cells. The StemCellNet web-interface has various easy-to-use tools for selection and prioritization of network components, as well as for integration of expression data provided by the user. As a unique feature, the networks generated can be screened

SUBMITTER: Pinto JP 

PROVIDER: S-EPMC4086070 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature